Done it on other engines.
If the chamber doesn't "break free" and is coming out hard, I suggest putting an impact wrench on it and rattling it back in and then out a little at a time to avoid taking all the threads out of the head. If you do, you can put in a helicoil insert.
Old style chambers has a separate "retainer" that sealed around the top of the chamber in the head. There were o-rings inside next to the PC chamber and outside next to the head. The retainer can be removed, resealed and replaced without disturbing the PC chamber itself with the correct set of tools. If you are dealing with this type and do not have compression leaking into the cooling system, I would leave the chambers alone just to avoid the possibility of damaging the threads.
Newer chambers are one piece and have only the copper washers on the bottom and the outer o-ring around the top. They must be removed to reseal the o-ring.